Steroid molecule diffusion

Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.

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12 th Pharmaceutical Sciences and Pharma Industry Conference February 26-27, 2018, London , UK; 7th European Biosimilars Conference , April 26-27, 2018, Rome, Italy ; 10 th Pharmacology Conferences during July 30-Aug 01, 2018 at Barcelona, Spain ; 4 th Marine Drugs and Natural Products Conferences , June 11-13, 2018 at Rome , Italy; 8 th Environmental Chemistry Conference , September 20-22, 2018 Berlin, Germany ; 9 th Pharmacovigilance Exhibition , June 21-22, 2018 at London, UK ; 4 th Antibiotics Conference ; June 14-15, 2018, Barcelona , Spain

Steroid molecule diffusion

steroid molecule diffusion

12 th Pharmaceutical Sciences and Pharma Industry Conference February 26-27, 2018, London , UK; 7th European Biosimilars Conference , April 26-27, 2018, Rome, Italy ; 10 th Pharmacology Conferences during July 30-Aug 01, 2018 at Barcelona, Spain ; 4 th Marine Drugs and Natural Products Conferences , June 11-13, 2018 at Rome , Italy; 8 th Environmental Chemistry Conference , September 20-22, 2018 Berlin, Germany ; 9 th Pharmacovigilance Exhibition , June 21-22, 2018 at London, UK ; 4 th Antibiotics Conference ; June 14-15, 2018, Barcelona , Spain

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